Desensitization of the cough reflex by exercise and voluntary isocapnic hyperpnea

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Desensitization of the cough reflex by exercise and voluntary isocapnic hyperpnea.

Little is known about the effects of exercise on the sensory and cognitive aspects of coughing evoked by inhalation of tussigenic agents. The threshold for the cough reflex induced by inhalation of increasing nebulizer outputs of ultrasonically nebulized distilled water (fog), an index of cough reflex sensitivity, was assessed in twelve healthy humans in control conditions, during exercise and ...

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Lack of desensitization of the cough reflex in ovalbumin-sensitized rabbits during exercise

INTRODUCTION Cough is a major symptom of asthma frequently experienced during exercise but little is known about interactions between cough and exercise. The goal of our study was to clarify the potential modulation of the cough reflex (CR) by exercise in a spontaneously breathing anaesthetized animal model of airway eosinophilic inflammation. MATERIALS & METHODS Ten ovalbumin (OVA) sensitize...

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Comparison of voluntary and reflex cough effectiveness in Parkinson's disease.

INTRODUCTION Multiple airway protective mechanisms are impacted with Parkinson's disease (PD), including swallowing and cough. Cough serves to eject material from the lower airways, and can be produced voluntarily (on command) and reflexively in response to aspirate material or other airway irritants. Voluntary cough effectiveness is reduced in PD however it is not known whether reflex cough is...

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Intra-abdominal Pressures during Voluntary and Reflex Cough

BACKGROUND Involuntary coughing such as that evoked from the larynx, the laryngeal cough reflex (LCR), triggers a coordinated contraction of the thoracic, abdominal and pelvic muscles, which increases intra-abdominal pressure (IAP), displaces the diaphragm upwards and generates the expiratory force for cough and airway clearance. Changes in the IAP during voluntary cough (VC) and the LCR can be...

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COUGH Differences in motor activation of voluntary and reflex cough in humans

Objectives: To study motor activation patterns of voluntary and reflex cough adjusted for cough flow rates. Methods: Surface electromyography (EMG) and cough flow rate were measured in 10 healthy volunteers. Voluntary cough was assessed for 20 efforts in each quintile of increasing cough flow rate. Reflex cough was assessed for 25 efforts produced by nebulised L-tartaric acid. EMG was recorded ...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2010

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.00423.2009